Maria Gaetana Agnesi. A heroin of advanced calculus. Am I a nerd or what!
A woman with it all - beauty, brains, international acclaim, and she discovered a little curve that has implications today in mathematical patterns (this is the "Witch" - the nickname it got)
But best of all, Maria found that she really just wanted to devote her life to helping the poor, of which there were a lot in the 18th century.